The use of radiofrequency ablation (RFA) for the treatment of large, benign thyroid nodules, a common practice in other countries but not endorsed in the United States, substantially and safely reduces nodule volume without compromising thyroid function, according to a retrospective review of patients at the Mayo Clinic.

“The present experience confirms that ultrasound-guided RFA is a clinically effective and safe outpatient treatment in patients with symptomatic or steadily growing benign, large, predominantly solid thyroid nodules, reproducing the experience generated in European and Asian studies,” the authors write.

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